Heleo 4 - Photodynamic Therapy 

Heleo 4®

Heleo 4® is a photodynamic therapy protocol that combines the application of a photosensitizing gel based on aminolevulinic acid with subsequent exposure to broad-spectrum intense pulsed light (IPL).

The active compound selectively accumulates in altered cells, including sebocytes, inflammatory acne lesions, and pigmented structures. When activated by light energy, it initiates a photochemical reaction that destroys pathologically altered tissue while largely preserving healthy epidermal cells.

At the «Искусство» clinic, photodynamic therapy is performed within a medical treatment protocol. A dermatologist and cosmetic physician evaluate the condition of the skin, exclude contraindications, and individually select treatment parameters. Heleo 4® is considered a therapeutic procedure with measurable clinical outcomes rather than a conventional cosmetic treatment.

Indications for Heleo 4® Photodynamic Therapy

Photodynamic therapy may be recommended for:

• Moderate and severe acne vulgaris, including inflammatory papules, pustules, and nodules
• Seborrhea and enlarged pores associated with hyperactivity of the sebaceous glands
• Post-acne manifestations, including persistent redness and uneven skin texture
• Signs of photoaging, such as pigmentation, solar lentigines, and fine wrinkles
• Facial telangiectasias
• Actinic keratosis (upon physician recommendation)
• Dull complexion and uneven skin tone

How the Procedure Is Performed

The treatment consists of several consecutive stages and usually takes between 60 and 90 minutes.

Skin Preparation

The skin is thoroughly cleansed.

If necessary, a superficial peel may be performed to enhance penetration of the photosensitizer.

A photosensitizing gel is then applied to the treatment area.

The incubation period lasts approximately 30–45 minutes, allowing the active compound to accumulate within target cells.

Light Activation

After incubation, IPL treatment is performed.

Parameters including wavelength range, fluence, and spot size are selected individually according to skin type and treatment goals.

Patients typically experience warmth and mild tingling during the procedure.

Topical anesthesia is rarely required.

After the Procedure

Mild redness and slight swelling may occur and usually resolve within 24–48 hours.

Strict ultraviolet protection and daily use of SPF 50+ sunscreen are mandatory during the first two days after treatment.

Results and Treatment Course

Visible improvements, including a reduction in inflammatory lesions and a more even complexion, are often observed after one or two sessions.

The full effect is generally assessed four to six weeks after completion of the treatment course.

Skin commonly appears clearer, smoother, and less oily, while pigmentation becomes lighter.

For acne, a standard course consists of three to five sessions performed every three to four weeks.

For photoaging and pigmentation concerns, two to three procedures are often sufficient.

Results may last from six to eighteen months depending on individual characteristics and adherence to the recommended skincare regimen.

The exact number of sessions is determined by the physician during consultation.

Contraindications

Photodynamic therapy is generally contraindicated in patients with:

• Pregnancy or breastfeeding
• Hypersensitivity to photosensitizing agents or IPL exposure
• Porphyria and disorders of porphyrin metabolism
• Use of photosensitizing medications, including tetracycline antibiotics and retinoids
• Active oncological treatment
• Acute inflammatory skin conditions in the treatment area
• Recent tanning or significant sun exposure within the previous two weeks
• Epilepsy, due to potential sensitivity to light flashes

A complete list of contraindications is established during medical consultation.

Frequently Asked Questions

Is Heleo 4® Painful?

Most patients describe the sensation as warmth accompanied by mild tingling during each light pulse.

Sensitivity varies from person to person.

If necessary, treatment intensity can be adjusted, or a topical anesthetic cream may be applied.

How Many Sessions Are Needed for Acne?

A standard treatment course consists of three to five sessions.

Mild acne may improve after two procedures, whereas more severe forms can require up to six sessions.

The treatment plan is always individualized.

Can Heleo 4® Be Combined with Other Procedures?

Yes.

Photodynamic therapy can be combined with superficial peels, mesotherapy, and professional skincare programs provided appropriate intervals are maintained.

Combining Heleo 4® with aggressive laser resurfacing procedures during the same treatment period is generally not recommended.

Is Special Preparation Required?

Patients should avoid intensive sun exposure for two weeks before treatment and refrain from aggressive chemical peels for approximately one week.

It is important to inform the physician about all medications being taken.

Detailed preparation instructions are provided during consultation.

Is There a Recovery Period?

Downtime is minimal.

Redness and mild swelling typically resolve within 24–48 hours.

Direct sun exposure should be avoided for the first two days, and SPF 50+ sunscreen should be used consistently.

Decorative cosmetics may usually be applied the following day if there is no significant skin reaction.

Book a Consultation

Book a consultation to determine whether Heleo 4® photodynamic therapy is appropriate for your skin concerns. Your physician will evaluate your skin condition and develop an individualized treatment plan.